Author: Alex Thompson

Avastin Bevacizumab: Side Effects, Uses, Dosage, Interactions, Warnings

what is the drug avastin

Mild side effects of many drugs may go away within a few days to a couple of weeks. But if they become bothersome, talk with your doctor or pharmacist. Avastin can increase the risk of developing congestive heart failure. Advise patients to contact their healthcare provider immediately for signs and symptoms of CHF [see WARNINGS AND PRECAUTIONS].

  1. They’ll discuss with you the risks and benefits of using Avastin.
  2. Serious side effects from Avastin can occur, but they aren’t common.
  3. You may wonder how Avastin compares with similar drugs, such as Eylea.
  4. Because of this, you should call your doctor right away if you have blurry vision while you’re taking Avastin.

They may recommend that you use a different cancer drug during pregnancy. Avastin begins working as soon as you take your first dose. But you may not feel any different after you’ve taken a dose, because the drug doesn’t treat any symptoms caused by your cancer.

The virus is in the baby’s poo for about 2 weeks and could make you ill if your immunity is low. Get someone else to change their nappies during this time if you can. If this isn’t possible, wash your hands well after changing their nappy. In the UK, live vaccines include rubella, mumps, measles, BCG, yellow fever and one of the shingles vaccines called Zostavax.

In addition, Eylea is approved to treat retinopathy of prematurity in infants. With this condition, atypical blood vessels grow in the retinas of babies born prematurely. As with most drugs, some people can have an allergic reaction after taking Avastin.

To learn more about our Avastin Access Solutions programs and services, call ( 249-4918.

According to the drug’s manufacturer, you’ll need to wait at least 28 days after having surgery before you start Avastin treatment. And before Avastin can be used, any wounds you have must be fully healed. According to the drug’s manufacturer, Avastin treatment can be continued as long as you aren’t having severe or very bothersome side effects. Eylea also comes as a solution that’s given as an intravitreal injection by specially trained doctors. Avastin and Temodar have different approved uses, but they’re both used to treat glioblastoma, which is a certain type of brain cancer.

what is the drug avastin

Avastin is not indicated for adjuvant treatment of colon cancer [see Clinical Studies]. Avastin (bevacizumab) injection for intravenous use is a sterile, clear to slightly opalescent, colorless to pale brown solution. Avastin is supplied in 100 mg and 400 mg preservative-free, single-dose vials to deliver 4 mL or 16 mL of Avastin (25 mg/m2L).

Avastin Images

The interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in in vitro models of angiogenesis. Administration of bevacizumab to xenotransplant models of colon cancer in nude (athymic) mice caused reduction of microvascular growth and inhibition of metastatic disease progression. Monitor blood pressure every two to three weeks during treatment with Avastin. Treat with appropriate anti-hypertensive therapy and monitor blood pressure regularly. Continue to monitor blood pressure at regular intervals in patients with Avastin-induced or -exacerbated hypertension after discontinuing Avastin.

The manufacturer of Avastin hasn’t given birth control recommendations for males using the drug. If you’re a male using Avastin and you’re sexually active with someone who’s able to become pregnant, talk with your doctor about your birth control needs while using this drug. In animal studies, Avastin caused low birth weights in offspring exposed to the drug during pregnancy.

The recommended dosage is 10 mg/kg intravenously every 2 weeks in combination with paclitaxel, pegylated liposomal doxorubicin, or topotecan (every week). The recommended dosage is 15 mg/kg intravenously every 3 weeks in combination with paclitaxel and cisplatin or in combination with paclitaxel and topotecan. Avastin should be used only when prescribed during pregnancy. Women of child-bearing age should use an effective form of birth control while using this medication and for an extended period after stopping this drug. Based on information from related drugs, this medication may pass into breast milk. Breastfeeding while using this medication is not recommended.

Alternatives for kidney cancer

In comparison, half of the people who didn’t take Avastin lived at least 10.3 months. Compared with small cell lung cancer (SCLC), NSCLC is typically a less aggressive form of lung cancer. Specifically, half of the people taking Avastin with chemotherapy went at least 4.2 months without their tumor progressing. In comparison, half of the people taking lomustine alone went at least 1.5 months without their tumor progressing. Other drugs may interact with bevacizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other cancer treatments you are receiving.

If you drink alcohol, talk with your doctor about the amount that’s safe for you to drink while during Avastin treatment. For details about what to expect with Avastin infusions, talk with your doctor. In addition to treating glioblastoma, which is described directly above, Avastin is also used for other types of cancer. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist.

Avastin contains the drug bevacizumab, which is a biologic drug. Advise patients to contact their healthcare provider immediately for signs or symptoms of infusion-related reactions [see WARNINGS AND PRECAUTIONS]. Avastin increases the risk of arterial and venous thromboembolic events. Advise patients to immediately contact their healthcare provider for signs and symptoms of arterial or venous thromboembolism [see WARNINGS AND PRECAUTIONS].

For details on how the drug performed in studies, see Avastin’s prescribing information. If you have high blood pressure during Avastin treatment, your doctor will likely have you stop receiving the drug temporarily. Once your blood pressure is managed, they may have you start Avastin treatment again. Or they may prescribe a different drug that doesn’t affect your blood pressure.